Type 2 Diabetes in Youth and Adults: New Insights Into the Pathogenesis Steven E. Kahn, M.B., Ch.B. Professor of Medicine Leonard L. Wright and Marjorie C. Wright Chair Division of Metabolism, Endocrinology and Nutrition Director, Diabetes Research Center University of Washington and VA Puget Sound Health Care System Glucose Signaling in Glucose Homeostasis and Feeding Behavior Bernard Thorens, Ph.D. Professor, Faculty of Biology and Medicine University of Lausanne, Switzerland The Joslin 50 Year Medalist Study: Identification of tissue protective factors in the retina, kidney and may be the β-cells George L. King, M.D. Chief Scientific Director, Joslin Diabetes Center Professor of Medicine & Opthalmology, Harvard Medical School Immunotherapy for Type 1 Diabetes Jay S. Skyler, M.D., MACP Professor of Medicine, Pediatrics & Psychology Deputy Director, Diabetes Research Institute University of Miami Moving to fully automated insulin delivery Bruce A. Buckingham, M.D. Professor of Pediatrics Division of Endocrinology & Diabetes Stanford The Road to a Cure Recent and Anticipated Advances Leading to a Cure in Diabetes ROUNDTABLE DISCUSSION